article

Neurospora msh4 ortholog confirmed by split-marker deletion

Authors

• • Sue Conway
  • Flinders University
• • Fred Bowring
  • Flinders University
• • Jane Yeadon
  • Flinders University
• • David Catcheside
  • Flinders University

Abstract

Although most eukaryotes have both MSH4 and MSH5 orthologs, Neurospora was initially thought to lack msh-4. We have deleted the most likely msh-4 candidate and observed a delay in the sexual cycle, disruption to meiosis and a reduction in fertility. Deletion is dominant, showing msh-4 is subject to MSUD. We conclude that Neurospora has a MSH4 ortholog and that it may have remained undetected because of an unusually high number of introns.

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How to Cite: Conway, S. , Bowring, F. , Yeadon, J. & Catcheside, D. (2006) “Neurospora msh4 ortholog confirmed by split-marker deletion”, Fungal Genetics Reports. 53(1). doi: https://doi.org/10.4148/1941-4765.1105